IGFBP1
جين من أنواع جينات الإنسان العاقل
IGFBP1 (Insulin like growth factor binding protein 1) هوَ بروتين يُشَفر بواسطة جين IGFBP1 في الإنسان.[1][2]
الوظيفة
عدلهذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
عدلهذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
عدل- ^ Brinkman A، Groffen C، Kortleve DJ، Geurts van Kessel A، Drop SL (يناير 1989). "Isolation and characterization of a cDNA encoding the low molecular weight insulin-like growth factor binding protein (IBP-1)". EMBO J. ج. 7 ع. 8: 2417–23. PMC:457109. PMID:2461294.
- ^ "Entrez Gene: IGFBP1 insulin-like growth factor binding protein 1". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
عدل- Rajaram S، Baylink DJ، Mohan S (1998). "Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions". Endocr. Rev. ج. 18 ع. 6: 801–31. DOI:10.1210/er.18.6.801. PMID:9408744.
- Ferry RJ، Cerri RW، Cohen P (1999). "Insulin-like growth factor binding proteins: new proteins, new functions". Horm. Res. ج. 51 ع. 2: 53–67. DOI:10.1159/000023315. PMID:10352394.
- Firth SM، Baxter RC (2003). "Cellular actions of the insulin-like growth factor binding proteins". Endocr. Rev. ج. 23 ع. 6: 824–54. DOI:10.1210/er.2001-0033. PMID:12466191.
- Wood AW، Duan C، Bern HA (2005). "Insulin-like growth factor signaling in fish". Int. Rev. Cytol. ج. 243: 215–85. DOI:10.1016/S0074-7696(05)43004-1. PMID:15797461.
- Ehrenborg E، Larsson C، Stern I، وآخرون (1992). "Contiguous localization of the genes encoding human insulin-like growth factor binding proteins 1 (IGBP1) and 3 (IGBP3) on chromosome 7". Genomics. ج. 12 ع. 3: 497–502. DOI:10.1016/0888-7543(92)90440-4. PMID:1373120.
- Ekstrand J، Ehrenborg E، Stern I، وآخرون (1990). "The gene for insulin-like growth factor-binding protein-1 is localized to human chromosomal region 7p14-p12". Genomics. ج. 6 ع. 3: 413–8. DOI:10.1016/0888-7543(90)90470-F. PMID:1691735.
- Suwanichkul A، Cubbage ML، Powell DR (1991). "The promoter of the human gene for insulin-like growth factor binding protein-1. Basal promoter activity in HEP G2 cells depends upon liver factor B1". J. Biol. Chem. ج. 265 ع. 34: 21185–93. PMID:1701175.
- Brinkman A، Kortleve DJ، Schuller AG، وآخرون (1991). "Site-directed mutagenesis of the N-terminal region of IGF binding protein 1; analysis of IGF binding capability". FEBS Lett. ج. 291 ع. 2: 264–8. DOI:10.1016/0014-5793(91)81298-M. PMID:1718783.
- Brewer MT، Stetler GL، Squires CH، وآخرون (1988). "Cloning, characterization, and expression of a human insulin-like growth factor binding protein". Biochem. Biophys. Res. Commun. ج. 152 ع. 3: 1289–97. DOI:10.1016/S0006-291X(88)80425-X. PMID:2454104.
- Julkunen M، Koistinen R، Aalto-Setälä K، وآخرون (1988). "Primary structure of human insulin-like growth factor-binding protein/placental protein 12 and tissue-specific expression of its mRNA". FEBS Lett. ج. 236 ع. 2: 295–302. DOI:10.1016/0014-5793(88)80041-3. PMID:2457513.
- Lee YL، Hintz RL، James PM، وآخرون (1988). "Insulin-like growth factor (IGF) binding protein complementary deoxyribonucleic acid from human HEP G2 hepatoma cells: predicted protein sequence suggests an IGF binding domain different from those of the IGF-I and IGF-II receptors". Mol. Endocrinol. ج. 2 ع. 5: 404–11. DOI:10.1210/mend-2-5-404. PMID:2458522.
- Luthman H، Söderling-Barros J، Persson B، وآخرون (1989). "Human insulin-like growth-factor-binding protein. Low-molecular-mass form: protein sequence and cDNA cloning". Eur. J. Biochem. ج. 180 ع. 2: 259–65. DOI:10.1111/j.1432-1033.1989.tb14641.x. PMID:2466665.
- Cubbage ML، Suwanichkul A، Powell DR (1989). "Structure of the human chromosomal gene for the 25 kilodalton insulin-like growth factor binding protein". Mol. Endocrinol. ج. 3 ع. 5: 846–51. DOI:10.1210/mend-3-5-846. PMID:2474129.
- Alitalo T، Kontula K، Koistinen R، وآخرون (1989). "The gene encoding human low-molecular weight insulin-like growth-factor binding protein (IGF-BP25): regional localization to 7p12-p13 and description of a DNA polymorphism". Hum. Genet. ج. 83 ع. 4: 335–8. DOI:10.1007/BF00291377. PMID:2478445.
- Brinkman A، Groffen CA، Kortleve DJ، Drop SL (1989). "Organization of the gene encoding the insulin-like growth factor binding protein IBP-1". Biochem. Biophys. Res. Commun. ج. 157 ع. 3: 898–907. DOI:10.1016/S0006-291X(88)80959-8. PMID:2849945.
- Busby WH، Klapper DG، Clemmons DR (1988). "Purification of a 31,000-dalton insulin-like growth factor binding protein from human amniotic fluid. Isolation of two forms with different biologic actions". J. Biol. Chem. ج. 263 ع. 28: 14203–10. PMID:2971653.
- Grundmann U، Nerlich C، Bohn H، Rein T (1988). "Cloning of cDNA encoding human placental protein 12 (PP12): binding protein for IGF I and somatomedin". Nucleic Acids Res. ج. 16 ع. 17: 8711. DOI:10.1093/nar/16.17.8711. PMC:338590. PMID:3419931.
- Jones JI، Gockerman A، Busby WH، وآخرون (1993). "Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence". Proc. Natl. Acad. Sci. U.S.A. ج. 90 ع. 22: 10553–7. DOI:10.1073/pnas.90.22.10553. PMC:47815. PMID:7504269.
- Jones JI، Busby WH، Wright G، وآخرون (1993). "Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1. Regulation of its affinity by phosphorylation of serine 101". J. Biol. Chem. ج. 268 ع. 2: 1125–31. PMID:7678248.